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Anti-biotic resistance in India (Relevant for GS Prelims, GS Mains Paper III)

A woman in the U.S. died after being infected by a superbug during her visit to India, say doctors who found that the “nightmare” bacteria was resistant to all available antibiotics.
The infection was caused by carbapenem-resistant Enterobacteriaceae (CRE), a multidrug-resistant organism associated with high mortality.

Background
The 70-year-old patient was admitted to an acute care hospital last year after an extended trip to India. She was given a primary diagnosis of serious infection called Klebsiella pneumoniae; none of the 14 antibiotics physicians used to treat the woman worked.

NDM-1 : Resistant to all anti-biotics
That testing confirmed the presence of New Delhi metallo-beta-lactamase (NDM-1), an enzyme that directly breaks down carbapenems, a powerful class of antibiotics that are often used to treat multidrug-resistant infections. The U.S. Centres for Disease Control and Prevention’s antimicrobial testing showed the isolate was resistant to 26 different antibiotics.



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